∙ Linear Channels
∙ Bifurcating Channels
∙ Microvascular Networks
∙ Idealized Networks
∙ Linear Channels
∙ Bifurcating Channels
∙ Microvascular Networks
∙ Idealized Networks
Three channels per chip of various widths to allow you to study shear effects based on channel size and flow rates.
Standard Width Options (W1 / W2 / W3):
∙ 100 μm / 100 μm / 100 μm
∙ 250 μm / 250 μm / 250 μm
∙ 500 μm / 500 μm / 500 μm
∙ 100 μm / 250 μm / 500 μm
Custom designs/sizes also available.
With various options of symmetric and asymmetric bifurcating angles and parent/daughter channel widths you can likely find a set of designs to provide you the best models for your research.
Standard Symmetric Bifurcation Angle (θB/θC) Options:
∙ 15° + 15°
∙ 30° + 30°
∙ 45° + 45°
∙ 60° + 60°
Custom designs/sizes also available.
Network 001, 100μm depth
SMN1-C001 (104001)
Network 002, 100μm depth
SMN1-D001 (104002)
Network 003, 100μm depth (M#55)
SMN1-C002 (104003)
Network 004, 100μm depth (M#55)
SMN1-C003 (104004)
Network 005, 100μm depth (M#55)
SMN1-C004 (104005)
Network 006, 100μm depth (M#55)
SMN1-C005 (104006)
Network 007, 100μm depth (M#55)
SMN1-C006 (104007)
Network 008, 100μm depth (M#55)
SMN1-C007 (104008)
Network 009, 100μm depth (M#56)
SMN1-D002 (104009)
Network 010, 100μm depth (M#56)
SMN1-D003 (104010)
Network 011, 100μm depth (M#56)
SMN1-D004 (104011)
Network 012, 100μm depth (M#56)
SMN1-D005 (104012)
Network 013, 100μm depth (M#56)
SMN1-D006 (104013)
Network 014, 100μm depth (M#56)
SMN1-D007 (104014)
By incorporating natural tissue regions within the network topology, the co-culture networks allow study of cell and drug behavior at and across the interfaces. The co-culture network constructs are available with several options for channel size, tissue region scaffolding, and barrier design. We can help you select the right parameters for your needs and can also construct custom designs if needed.
3 um Height Barrier: 10um Dia-50um Separation, 100 um Depth
SMN2-C001 (105001)
3 um Height Barrier: 10um Dia-50um Separation, 100 um Depth
SMN2-D001 (105002)
Use these chips for studies of tumor microenvironment based on differential flow gradients and metastasis.
SMN3-C002 (106009)
SMN3-D002 (106010)
Tandem chips are designed with synthetic tumor networks comprising primary and secondary tumor sites. This chip has been used to develop a 3D vascularized model for monitoring the invasive growth patterns and metastatic potential of tumors, thereby mimicking both the in vivo microenvironment of solid tumors, cancer invasion and metastasis. This model can be used to investigate tumor-endothelial cell interactions using a combination of real-time imaging techniques and screening of targeted therapeutics that may reduce the metastatic potential of tumors.
SMN3-JN1-100 (106013)
Intended to mimic the formation of and transport across tight and gap junctions such as the blood-brain barrier and other endothelial/tissue interfaces, the idealized co-culture constructs are available with several options for channel size, tissue chamber size and scaffolding, and barrier design. We can help you select the right parameters for your needs and can also construct custom designs if needed. Please contact us for details.
These device utilizes slits and gaps to form the barrier region between the outer channel and inner chamber.
∙ Outer Channel Width (OC): 100 μm or 200 μm
∙ Travel Width (T): 50 μm or 100 μm
∙ Slit Spacing (SS): 50 μm or 100 μm
∙ Slit Width (WS): Variable
IMN2 Slit/Pillar
IMN2/3 Slit
IMN2 Pillar
IMN2/3 Slit Detail
IMN2 Pillar Detail
These devices utilize pillars to form the barrier region between the outer channel and inner chamber.
∙ Outer Channel Width (OC): 100 μm or 200 μm
∙ Travel Width (T): 50 μm or 100 μm
∙ Pillar Spacing (Gap) (SP): 8μm or 3μm
∙ Pillar Diameter (DP): Variable
∙ Pore sizes available 3μm or 8μm
IMN2 Slit/Pillar
IMN2/3 Slit
IMN2 Pillar